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1 Study StatusActive, not recruiting1 A clinical trial to compare GDC-9545 with a doctor’s choice of hormonal therapy in people with advanced or metastatic breast cancer after previous treatment has not worked.
A Study Evaluating the Efficacy and Safety of GDC-9545 Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
- Cancer,
- Breast Cancer,
- Breast Cancer Er-Positive,
- Breast Cancer HER-2 Negative,
- Locally Advanced or Metastatic Breast Cancer,
- Estrogen Receptor (ER)-Positive
- NCT04576455, WO42312, 2020-001984-10
2 Study StatusActive, not recruiting2 A study to look at how safe emicizumab treatment is and how well it works to prevent bleeds in children with haemophilia A (without factor 8 inhibitors) who started emicizumab in their first year of life
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors
- Hemophilia,
- Hemophilia A,
- Severe Hemophilia A
- NCT04431726, MO41787, 2020-001733-12,2023-505964-13-00
3 Study StatusActive, not recruiting3 A clinical trial to compare tiragolumab plus atezolizumab and bevacizumab with placebo plus atezolizumab and bevacizumab in people with untreated, advanced hepatocellular carcinoma
A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (IMbrave152)
- Cancer,
- Hepatocellular Carcinoma (HCC)
- NCT05904886, CO44668, 2023-503422-39-00
4 Study StatusActive, not recruiting4 A study to look at the effects of different treatments on rare types of previously treated epithelial ovarian, fallopian tube or primary peritoneal cancers with different molecular changes
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
- Cancer,
- Ovarian Cancer
- NCT04931342, WO42178, GOG-3051, ENGOT-GYN2
5 Study StatusActive, not recruiting5 A study evaluating the efficacy and safety of neoadjuvant treatment with atezolizumab or placebo in combination with platinum-based chemotherapy in patients with resectable stage II, IIIA, or select IIIB non-small cell lung cancer
A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)
- Cancer,
- Lung Cancer,
- Non-Small Cell Lung Cancer (NSCLC)
- NCT03456063, GO40241, 2023-504209-35-00
6 Study StatusActive, not recruiting6 A clinical trial to look at how well obinutuzumab works in treating people with lupus nephritis and how safe it is (REGENCY)
A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis
- Autoimmune Disorder,
- Lupus Nephritis
- NCT04221477, CA41705, 2019-004034-42
7 Study StatusActive, not recruiting7 A clinical trial to compare tobemstomig with pembrolizumab in combination with nab-paclitaxel in people with untreated breast cancer
A Study of Tobemstomig + Nab-Paclitaxel Compared With Pembrolizumab + Nab-Paclitaxel in Participants With Previously Untreated, PD-L1-Positive, Locally-Advanced Unresectable or Metastatic Triple-Negative Breast Cancer
- Cancer,
- Breast Cancer,
- Triple Negative Breast Cancer
- NCT05852691, CO44194, 2022-502457-34-00
8 Study StatusActive, not recruiting8 A clinical trial to look at how safe emicizumab is in patients with mild or moderate hemophilia A, and how emicizumab affects bleeding in this patient population.
A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors
- Hemophilia,
- Hemophilia A
- NCT04158648, BO41423, 2023-506610-52-00
9 Study StatusActive, not recruiting9 A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
- Cancer,
- Breast Cancer,
- Breast Cancer Er-Positive,
- Breast Cancer HER-2 Negative,
- Locally Advanced or Metastatic Breast Cancer,
- Estrogen Receptor (ER)-Positive
- NCT05306340, ML43171, 2022-000199-20,2023-506821-12-00
10 Study StatusActive, not recruiting10 A clinical trial to compare inavolisib plus fulvestrant versus alpelisib plus fulvestrant in people with hormone receptor-positive, HER2-negative, PIK3CA-mutated breast cancer that has spread during or after treatment with a CDK4/6 inhibitor plus hormone (endocrine) therapy
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
- Cancer,
- Breast Cancer,
- Breast Cancer Er-Positive,
- Breast Cancer HER-2 Negative
- NCT05646862, WO43919, 2022-502322-41-00