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We found 59 Results.Use the filters to narrow down your search.
1 
Study StatusRecruiting1 A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
- Cancer,
- Breast Cancer,
- Early Breast Cancer,
- Breast Cancer Er-Positive,
- Breast Cancer HER-2 Negative
- NCT04961996, GO42784, 2021-000129-28,2023-507172-44-00
2 Study StatusRecruiting2 A clinical trial to see how well different doses of astegolimab plus standard treatment work compared with a placebo plus standard treatment to reduce certain symptoms of chronic obstructive pulmonary disease
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
- Respiratory Disorder,
- Chronic Obstructive Pulmonary Disease (COPD)
- NCT05595642, GB44332
3 Study StatusRecruiting3 A clinical trial to understand how genetic testing can help doctors to decide which treatment is best for patients with solid tumours (TAPISTRY)
Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
- Cancer,
- Solid Tumors
- NCT04589845, BO41932, 2020-001847-16
4 Study StatusRecruiting4 A clinical trial to look at how safe astegolimab is when given over a long period of time for people with chronic obstructive pulmonary disease by measuring the number and seriousness of side effects
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
- Respiratory Disorder,
- Chronic Obstructive Pulmonary Disease (COPD)
- NCT05878769, GB43374, 2022-502501-15-00
5 Study StatusRecruiting5 A clinical study to compare giredestrant with fulvestrant, both combined with a targeted therapy (CDK4/6 inhibitor) in people with ER-positive, HER2-negative breast cancer that has come back after adjuvant hormone therapy
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
- Cancer,
- Breast Cancer,
- Breast Cancer HER-2 Negative,
- Estrogen Receptor (ER)-Positive
- NCT06065748, CO44657, 2022-502980-39-00
6 Study StatusRecruiting6 A clinical trial to compare RO7198574 plus inavolisib with RO7198574 plus placebo as maintenance treatment after first treatment in people with PIK3CA‑mutated HER2‑positive breast cancer that has grown (locally advanced) or spread (metastatic)
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
- Cancer,
- Breast Cancer,
- Breast Cancer Er-Positive,
- Metastatic Breast Cancer,
- HER2-Positive Breast Cancer
- NCT05894239, WO44263, 2022-502046-28-00
7 Study StatusRecruiting7 A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease
- Respiratory Disorder,
- Idiopathic Pulmonary Fibrosis (IPF),
- Systemic Sclerosis With Lung Involvement
- NCT05785624, GB44496, 2022-502828-42
8 Study StatusRecruiting8 A clinical trial to compare how effective and safe giredestrant plus pertuzumab and trastuzumab is compared to pertuzumab and trastuzumab with or without hormone therapy in people with locally advanced or metastatic breast cancer, with HER2 and oestrogen receptor positivity
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)
- Cancer,
- Oncology,
- Breast Cancer,
- Locally Advanced or Metastatic Breast Cancer,
- Estrogen Receptor (ER)-Positive,
- HER2-Positive Breast Cancer
- NCT05296798, WO43571, 2022-500014-26-00
9 Study StatusRecruiting9 A clinical trial to look at how safe different doses of RO7507062 are in people with systemic lupus erythematosus and how the body processes this drug
A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus
- Autoimmune Disorder,
- Systemic Lupus Erythematosus
- NCT05835986, BP44315, 2022-502632-39-00
10 Study StatusRecruiting10 A clinical trial to compare obinutuzumab with placebo in adolescents with lupus nephritis (POSTERITY)
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
- Autoimmune Disorder,
- Lupus Nephritis
- NCT05039619, WA42985, 2021-000097-29,2023-505825-15-00